Solid Tumor Therapy Using a Cannon and Pawn Combination Strategy
نویسندگان
چکیده
منابع مشابه
Solid Tumor Therapy Using a Cannon and Pawn Combination Strategy
Nanocarrier-based anti-tumor drugs hold great promise for reducing side effects and improving tumor-site drug retention in the treatment of solid tumors. However, therapeutic outcomes are still limited, primarily due to a lack of drug penetration within most tumor tissues. Herein, we propose a strategy using a nanocarrier-based combination of vascular disrupting agents (VDAs) and cytotoxic drug...
متن کاملThe Safety and Treatment Response of Combination Therapy of Radioimmunotherapy and Radiofrequency Ablation for Solid Tumor: A Study In Vivo
OBJECTION To investigate the safety and treatment response of radioimmunotherapy (RIT) in combination with radiofrequency ablation (RFA) for the treatment of VX2 tumor on rabbit. MATERIALS AND METHODS A total of 36 rabbits bearing VX2 tumor on the thigh were randomly assigned into 3 groups (group I: 1-2 cm; group II: 2-3 cm; group III: 3-4 cm) and 4 subgroups (A: as control, just puncture the...
متن کاملSolid Tumor Differentiation Therapy – Is It Possible?
Genetic and epigenetic events within a cell which promote a block in normal development or differentiation coupled with unregulated proliferation are hallmarks of neoplastic transformation. Differentiation therapy involves the use of agents with the ability to induce differentiation in cells that have lost this ability, i.e. cancer cells. The promise of differentiation-based therapy as a viable...
متن کاملNanomedicine-Mediated Combination Drug Therapy in Tumor
REVIEW ARTICLE Nanomedicine-Mediated Combination Drug Therapy in Tumor Dazhong Chen, Fangyuan Xie, Duxin Sun, Chuan Yin, Jie Gao and Yanqiang Zhong Department of Pharmaceutical Sciences, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China Department of Pharmaceu...
متن کاملCurrent status of therapy of solid tumors: brain tumor therapy.
Treatment of malignant brain tumors with conventional approaches is largely unsuccessful because curative doses generally cannot be delivered without excessive toxicity to normal brain. Radioimmunotherapy is emerging as an attractive alternative for glioma therapy because of the potential for more selectively irradiating tumor cells while sparing normal tissues. Several institutions are engaged...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Theranostics
سال: 2016
ISSN: 1838-7640
DOI: 10.7150/thno.14741